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存在抗人白细胞抗原(HL-A)抗体时血小板输注无效的不明原因。

Unrecognized causes of platelet transfusion failure in the presence of anti-HL-A antibodies.

作者信息

Hattersley P G

出版信息

West J Med. 1977 Apr;126(4):263-6.

Abstract

When in a patient who is receiving random donor platelet infusions there is an inadequate rise in platelet count and anti-human HL-A antibodies are noted in the serum, it is natural to assume that platelet destruction results from an immunologic cause. Nonimmunologic causes of such failure do occur, however. Two of the most common are disseminated intravascular coagulation and splenomegaly.

摘要

当接受随机供体血小板输注的患者血小板计数升高不足且血清中检测到抗人HL - A抗体时,自然而然会认为血小板破坏是由免疫原因导致的。然而,这种输注失败的非免疫原因确实存在。其中最常见的两种原因是弥散性血管内凝血和脾肿大。

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