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相似文献

1
Unrecognized causes of platelet transfusion failure in the presence of anti-HL-A antibodies.存在抗人白细胞抗原(HL-A)抗体时血小板输注无效的不明原因。
West J Med. 1977 Apr;126(4):263-6.
2
Heterogeneity of antibody response to human platelet transfusion.对人类血小板输注的抗体反应的异质性
J Clin Invest. 1976 Aug;58(2):432-8. doi: 10.1172/JCI108487.
3
The transfusion of HLA-matched platelets to thrombocytopenic patients resistant to random donor platelets.向对随机供者血小板产生抵抗的血小板减少症患者输注 HLA 匹配的血小板。
N Z Med J. 1984 Oct 24;97(766):719-21.
4
Alloimmunization to public HLA antigens in multi-transfused platelet recipients.多次输注血小板受者对公共HLA抗原的同种免疫。
Ann Clin Lab Sci. 1986 Jan-Feb;16(1):38-44.
5
[Experience of HLA-matched platelet transfusion in patients who are refractory to random donor platelets].[人类白细胞抗原(HLA)配型血小板输注对随机供者血小板输注无效患者的治疗经验]
Hokkaido Igaku Zasshi. 1988 Jul;63(4):552-61.
6
[Comparison of 4 crossmatching methods for predicting the success of platelet transfusion].
Beitr Infusionsther. 1990;26:153-6.
7
[Prevention of HLA-alloimmunization of recipients of platelet concentrates].[预防血小板浓缩物接受者的HLA同种免疫]
Beitr Infusionsther. 1991;28:209-12.
8
[Platelet alloimmunization in patients with oncologic blood disorders treated with multiple transfusions: prospective study in adults and children].[多次输血治疗的肿瘤血液疾病患者的血小板同种免疫:成人和儿童的前瞻性研究]
Rev Med Chil. 1997 Nov;125(11):1305-12.
9
[The effect of HLA alloimmunization and other factors on the effectiveness of thrombocyte concentrates].[人类白细胞抗原同种免疫及其他因素对血小板浓缩物有效性的影响]
Cas Lek Cesk. 1990 Jun 15;129(24):751-3.
10
The mechanism of platelet aggregation induced by HLA-related antibodies.HLA相关抗体诱导血小板聚集的机制。
Thromb Haemost. 1996 Nov;76(5):774-9.

本文引用的文献

1
A study of the haemorrhagic diathesis in leukaemia and allied diseases.白血病及相关疾病出血素质的研究
Can Med Assoc J. 1960 Sep 17;83(12):639-41.
2
Intravascular coagulation in acute leukemia: clinical and subclinical abnormalities.
Blood. 1972 Nov;40(5):709-18.
3
[Minimum consumption coagulopathies with normal or raised fibrinogen level].
Nouv Presse Med. 1973 Feb 24;2(8):512.
4
Acute promyelocytic leukemia: a model for understanding the role of the malignant cell in hemostasis.急性早幼粒细胞白血病:理解恶性细胞在止血中作用的模型。
Hum Pathol. 1974 Nov;5(6):661-73. doi: 10.1016/s0046-8177(74)80037-7.

存在抗人白细胞抗原(HL-A)抗体时血小板输注无效的不明原因。

Unrecognized causes of platelet transfusion failure in the presence of anti-HL-A antibodies.

作者信息

Hattersley P G

出版信息

West J Med. 1977 Apr;126(4):263-6.

PMID:855318
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1237540/
Abstract

When in a patient who is receiving random donor platelet infusions there is an inadequate rise in platelet count and anti-human HL-A antibodies are noted in the serum, it is natural to assume that platelet destruction results from an immunologic cause. Nonimmunologic causes of such failure do occur, however. Two of the most common are disseminated intravascular coagulation and splenomegaly.

摘要

当接受随机供体血小板输注的患者血小板计数升高不足且血清中检测到抗人HL - A抗体时,自然而然会认为血小板破坏是由免疫原因导致的。然而,这种输注失败的非免疫原因确实存在。其中最常见的两种原因是弥散性血管内凝血和脾肿大。