Bayer P M, Flegel U, Pointner H
Wien Klin Wochenschr. 1977 Apr 1;89(7):222-4.
19 Persons with gross refractory obesity (7 men and 12 women) were treated by therapeutic starvation. The patients were controlled after 32 months, on average (range: 7 to 58 months), following completion of treatment. The study shows that 8 of the females gained weight, one of these attaining her pretreatment weight and another even exceeding the pretreatment figure. None of the males had regained his pretreatment weight but 4 showed an increase in comparison with the weight at the time of hospital discharge. During starvation the serum lipids showed a marked decrease, which was statistically significant in the case of cholesterol, but not triglycerides. At the time of follow-up examination the serum lipid values were about the same as before treatment. It is concluded that the long-term results of therapeutic starvation are beter in men than in women and yet this method of treatment should be attempted, when indicated according to strict criteria, in refractory cases of extreme obesity.
19名严重难治性肥胖患者(7名男性和12名女性)接受了治疗性饥饿治疗。治疗结束后,平均在32个月(范围:7至58个月)后对患者进行了随访。研究表明,8名女性体重增加,其中1名恢复到治疗前体重,另1名甚至超过了治疗前体重。没有男性恢复到治疗前体重,但有4名男性与出院时的体重相比有所增加。饥饿期间,血脂显著下降,胆固醇下降具有统计学意义,但甘油三酯无明显下降。随访检查时,血脂值与治疗前大致相同。得出的结论是,治疗性饥饿的长期效果在男性中比在女性中更好,但在严格标准表明适应证的情况下,对于极端肥胖的难治性病例,仍应尝试这种治疗方法。