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[慢性心房颤动的治疗]

[The treatment of chronic atrial fibrillation].

作者信息

Gosselink A T

机构信息

Afdeling Cardiologie, Acadamisch Ziekenhuis Groningen.

出版信息

Tijdschr Gerontol Geriatr. 1995 Dec;26(6):259-63.

PMID:8553436
Abstract

Atrial fibrillation is a common arrhythmia. It is associated with increased morbidity and mortality, in part secondary to an increased rate of thromboembolism. Considering the arrhythmia's duration, a chronic and paroxysmal type can be recognized. Only the former will be discussed here. Treatment of atrial fibrillation should be aimed at restoring sinus rhythm. This may improve exercise tolerance and alleviate symptoms. In addition, it may obviate the need for antithrombotic therapy. Electrical cardioversion is the method of choice to restore sinus rhythm in patients with chronic atrial fibrillation. To prevent arrhythmia relapses, anti-arrhythmic drugs are often prescribed. These drugs, however, may have serious side effects, e.g. proarrhythmia. The pros and cons of antiarrhythmics should therefore be considered seriously before prescribing these drugs. An alternative strategy is to optimize ventricular rate response (usually pharmacologically) while the patient maintains in atrial fibrillation. To prevent thromboembolism, however, the use of antithrombotic is strongly recommended in most of these patients.

摘要

心房颤动是一种常见的心律失常。它与发病率和死亡率的增加相关,部分原因是血栓栓塞发生率的增加。考虑到心律失常的持续时间,可以识别出慢性和阵发性类型。这里仅讨论前者。心房颤动的治疗应以恢复窦性心律为目标。这可能会提高运动耐量并缓解症状。此外,它可能无需抗血栓治疗。电复律是恢复慢性心房颤动患者窦性心律的首选方法。为防止心律失常复发,常开具抗心律失常药物。然而,这些药物可能有严重的副作用,例如促心律失常作用。因此,在开具这些药物之前应认真考虑抗心律失常药物的利弊。另一种策略是在患者维持心房颤动状态时优化心室率反应(通常通过药物)。然而,为预防血栓栓塞,强烈建议大多数此类患者使用抗血栓药物。

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