Alferov V S, Akhundov A A, Pavlovskaia A I, Nikolaeva T G, Azizian R I, Zak K M, Rotobel'skaia L E
Vestn Otorinolaringol. 1995 Nov-Dec(6):27-31.
The study of morphological and biological criteria of laryngeal squamous cell carcinoma in 81 patients proved essential in the disease prognosis. In grade I malignancy 90 +/- 6.7% of patients were 3 years free of recurrences and metastases, in grade 11 - 76 +/- 8.6%, in grade III - 50 +/- 15.8%. Aneuploid laryngeal tumors produced recurrences 6 times more frequently than diploid ones. 3-year recurrence--and metastases-free survival was reported in 88.7 +/- 6.3% of patients with diploid and 59.3 +/- 7.7%. 7% with aneuploid tumors (p < 0.05).
对81例喉鳞状细胞癌患者的形态学和生物学标准进行研究,结果证明这对疾病预后至关重要。在I级恶性肿瘤中,90±6.7%的患者3年无复发和转移;在II级中为76±8.6%;在III级中为50±15.8%。非整倍体喉肿瘤复发的频率是二倍体肿瘤的6倍。二倍体患者3年无复发和转移生存率为88.7±6.3%,非整倍体肿瘤患者为59.3±7.7%,二者差异有统计学意义(p<0.05)。