Variability of polyploid strains of Candida scottii in accumulation of riboflavin in the medium.

Polyploid strains of Candida scottii show a higher spontaneous and UV-induced variability in accumulation of riboflavin in the medium than the original haploid strain. UV irradiation affects the formation of variants and induces those which accumulate more riboflavin than any of the most productive variants resulting from spontaneous variability. In the polyploid strains the frequency of plus-variants increases. Therefore, polyploid strains of C. scottii are advantageous for selection processes.