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[膀胱切除术后行盲肠膀胱扩大术:功能及肿瘤学结果。101例经验]

[Cystectomy followed by cecocystoplasty: functional and oncologic results. An experience of 101 cases].

作者信息

Rampal M, Bretheau D, Truong Thi T

机构信息

Service d'Urologie, Hôpital de la Timone, Marseille.

出版信息

Ann Urol (Paris). 1995;29(4):204-12.

PMID:8554291
Abstract

From 1979 to 1992, 101 radical cystectomy with caecoplasty were performed by the same operator (MR). Mean age of the patients was 62 years with a sex-ratio: 10 males/1 female. The indications were: Transitional Cell Carcinoma in 89 cases, neurologic bladder in 5 cases, interstitial cystitis in 3 cases tuberculosis bladder in 3 cases and lymphoma in one case. The operative mortality was 3% and postoperative morbidity was 8%. The surgical procedure consisted of performing a neo-bladder with ileocaecal segment. The technique of ureterocaecal implantation changed during the study period. On a functional point of view, 28 ureterocaecal stenosis were reported (15%). It were rare (2.4%) with the last ureterocaecal anastomosis technique. The diurnal continence rate was 100%. The nocturnal continence rate was only 25%. On uroflowmetric point of view, the detubularization permitted to obtain low pressure bladders with 15% rate of atonic bladder. Transverse taeniamyotomy of the caecum permitted to increase the uroflowmetric performance of the bladder without atonic risk. The 5 and 10 year overall actuarial survival rate were respectively 5% and 30%. Tumoral stage was a significant prognostic factor. An adjuvant chemotherapy was performed in 28 patients. The 5 year actuarial survival rate of the patients with a chemotherapy was 82% versus 28% for the patients without chemotherapy (p < 0.01). Caecocystoplasty after radical cystectomy was a reliable technique in our experience.

摘要

1979年至1992年期间,由同一位医生(MR)实施了101例根治性膀胱切除术并进行盲肠成形术。患者的平均年龄为62岁,男女比例为10∶1。手术适应证包括:89例移行细胞癌、5例神经源性膀胱、3例间质性膀胱炎、3例膀胱结核以及1例淋巴瘤。手术死亡率为3%,术后发病率为8%。手术步骤包括用回盲肠段构建新膀胱。在研究期间,输尿管盲肠植入技术发生了变化。从功能角度来看,报告有28例输尿管盲肠狭窄(15%)。采用最后一种输尿管盲肠吻合技术时狭窄情况较少见(2.4%)。日间控尿率为100%,夜间控尿率仅为25%。从尿流动力学角度来看,去管状化可使膀胱获得低压,无张力性膀胱发生率为15%。盲肠横行肌切开术可提高膀胱的尿流动力学性能且无张力风险。5年和10年的总精算生存率分别为5%和30%。肿瘤分期是一个重要的预后因素。28例患者接受了辅助化疗。接受化疗患者的5年精算生存率为82%,未接受化疗患者为28%(p<0.01)。根据我们的经验,根治性膀胱切除术后的盲肠膀胱成形术是一种可靠的技术。

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