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[免疫功能正常患者中枢神经系统原发性T细胞淋巴瘤。两例临床及病理研究]

[Primary T-cell lymphoma in the central nervous system of immunocompetent patients. Clinical and pathological study of two cases].

作者信息

Carod J, Eiras J, Alberdi J, Giménez-Mas J A, Fayed N, Mayayo P, Martínez D

机构信息

Servicio de Neurología, Hospital Miguel Servet, Zaragoza.

出版信息

Neurologia. 1995 Oct;10(8):346-9.

PMID:8554786
Abstract

Primary T-cell lymphoma in the central nervous system has rarely been described in the literature. We report 2 such cases in immunocompetent patients. The first presented with subacute encephalopathy affecting both memory and speech. A CT-scan of the head showed a contrast-enhanced mass around the third ventricle. The second presented with 2 partial seizures with secondary generalization; the CT-scan in this case showed a right temporal lesion. Both underwent surgery for total removal of the masses followed by cranial irradiation. Tissue examination confirmed the diagnosis. The first patient died 14 months after diagnosis. In the second case lymphoma recurred 8 months after surgery.

摘要

原发性中枢神经系统T细胞淋巴瘤在文献中鲜有描述。我们报告了2例免疫功能正常患者的此类病例。第一例表现为影响记忆和言语的亚急性脑病。头部CT扫描显示第三脑室周围有一个强化肿块。第二例表现为2次部分性发作继发全身性发作;该病例的CT扫描显示右侧颞叶有病变。两者均接受了手术以完全切除肿块,随后进行了颅脑照射。组织检查确诊。第一例患者在诊断后14个月死亡。第二例患者在手术后8个月淋巴瘤复发。

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