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[睡眠和清醒不同阶段的丘脑非特异性系统]

[Thalamo non-specific system at different stages of sleep and wakefulness].

作者信息

Burikov A A, Fel'dman G L

出版信息

Zh Vyssh Nerv Deiat Im I P Pavlova. 1977 Jan-Feb;27(1):177-85.

PMID:855480
Abstract

Cortical respones to low-frequency (6 to 8 per sec) rhythmic stimulation of the Centrum medianum thalami have been studied in chronic experiments on cats. Three types of recruiting reactions have been readily obtained: 1) with periodic spindling of response amplitudes, the sustained oscillatory type; 2) with spindling only at the beginning of stimulation, the decaying oscillatory type, and 3) with equal amplitudes throughout the stimulation, the aperiodic type. Distinct changes in the type of reactions have been shown--from the aperiodic to the sustained oscillatory type during transition of active awake state to slow-wave sleep, and from the sustained oscillatory type to the aperiodic type during transition of slow-wave sleep to the paradoxical sleep, which is due to changes in the weights of feedbacks in the thalamo-cortical nonspecific system.

摘要

在对猫的慢性实验中,研究了皮质对丘脑中央中核低频(每秒6至8次)节律性刺激的反应。很容易获得三种类型的募集反应:1)反应幅度呈周期性纺锤样变化,即持续振荡型;2)仅在刺激开始时出现纺锤样变化,即衰减振荡型;3)在整个刺激过程中幅度相等,即非周期性型。已表明反应类型有明显变化——在从清醒活跃状态过渡到慢波睡眠期间,从非周期性型转变为持续振荡型;在从慢波睡眠过渡到异相睡眠期间,从持续振荡型转变为非周期性型,这是由于丘脑 - 皮质非特异性系统中反馈权重的变化所致。

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