Gutiérrez Triguero M, Ramos Martínez M A, Bodoque Cano M, Escamilla Carpintero Y, Martínez Guirado T, Scola Pliego E
Servicio de ORL, Hospital Gregorio Marañón, Madrid.
Acta Otorrinolaringol Esp. 1995 Nov-Dec;46(6):447-52.
Wegener's granulomatosis (WG) is characterized by necrotizing granulomas and vasculitis that may affect any organ. The upper and lower respiratory tract and kidney usually are affected. WG is diagnosed by determination of anti-neutrophil cytoplasm antibody (ANCA), a highly sensitive and specific test that is particularly important in the early stages to achieve the best prognosis. We describe a case in a 28-year-old man that exemplifies some of the diagnostic features of WG.
韦格纳肉芽肿(WG)的特征是坏死性肉芽肿和血管炎,可累及任何器官。上、下呼吸道及肾脏常受累。WG通过检测抗中性粒细胞胞浆抗体(ANCA)来诊断,这是一项高度敏感且特异的检测,在早期阶段对于获得最佳预后尤为重要。我们描述了一名28岁男性的病例,该病例体现了WG的一些诊断特征。