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[脉冲剂量率居里疗法]

[Pulse dose rate curietherapy].

作者信息

Mazeron J J, Boisserie G, Baillet F

机构信息

Centre des tumeurs, groupe hospitalier Pitié-Salpêtrière, Paris, France.

出版信息

Bull Cancer Radiother. 1995;82(3):332-5.

PMID:8554884
Abstract

The pulse dose rate (PDR) afterloading system is a new afterloading system which operates on the pulsed brachytherapy principle. A typical pulse length is 10 minutes, increasing to approximately 30 minutes three months later as the iridium 192 source decays. The pulse treatment is repeated each hour. The source activity is 1 Ci or less and thus the system can be installed in shielded rooms suitable for low dose rate implants. The PDR afterloading system enables equivalent continuous low dose rate treatments to be given with all the advantages of a stepping source: only one source to replace once every three months (no source inventory required), no source preparation, programmable low dose rate, optimization of dose distribution, radiation protection, patient can be disconnected between pulses, intracavitary, interstitial, intraoperative, and intralumenal treatments feasible using a single afterloader.

摘要

脉冲剂量率(PDR)后装系统是一种基于脉冲近距离治疗原理运行的新型后装系统。典型的脉冲长度为10分钟,三个月后随着铱192源的衰变增加到约30分钟。每小时重复进行脉冲治疗。源活度为1居里或更低,因此该系统可安装在适合低剂量率植入的屏蔽室内。PDR后装系统能够进行等效的连续低剂量率治疗,并具有步进源的所有优点:每三个月只需更换一次源(无需源库存),无需源准备,可编程低剂量率,剂量分布优化,辐射防护,脉冲之间患者可断开连接,使用单个后装器可行腔内、间质、术中及腔内治疗。

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