Omeprazole does not affect measured CYP3A4 activity using the erythromycin breath test.
作者信息
Tateishi T, Graham S G, Krivoruk Y, Wood A J
出版信息
Br J Clin Pharmacol. 1995 Oct;40(4):411-2. doi: 10.1111/j.1365-2125.1995.tb04566.x.
Abstract
摘要
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Omeprazole does not affect measured CYP3A4 activity using the erythromycin breath test.使用红霉素呼气试验时，奥美拉唑不影响所测得的CYP3A4活性。
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本文引用的文献
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Identification of human liver cytochrome P450 isoforms mediating omeprazole metabolism.介导奥美拉唑代谢的人肝细胞色素P450同工酶的鉴定。
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Dose-ranging effects of candoxatril on elimination of exogenous atrial natriuretic peptide in chronic heart failure.坎多沙坦对慢性心力衰竭患者外源性心房利钠肽清除的剂量范围效应。
Clin Pharmacol Ther. 1993 Dec;54(6):661-9. doi: 10.1038/clpt.1993.204.
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Absence of correlations among three putative in vivo probes of human cytochrome P4503A activity in young healthy men.年轻健康男性体内三种假定的细胞色素P4503A活性探针之间不存在相关性。
Clin Pharmacol Ther. 1993 Dec;54(6):621-9. doi: 10.1038/clpt.1993.199.
5
Metabolism of cytochrome P4503A substrates in vivo administered by the same route: lack of correlation between alfentanil clearance and erythromycin breath test.经相同途径体内给药的细胞色素P4503A底物的代谢：阿芬太尼清除率与红霉素呼气试验之间缺乏相关性。
Clin Pharmacol Ther. 1994 Dec;56(6 Pt 1):608-14. doi: 10.1038/clpt.1994.185.
6
Characterization of cimetidine, ranitidine, and related structures' interaction with cytochrome P-450.西咪替丁、雷尼替丁及相关结构与细胞色素P-450相互作用的表征
Drug Metab Dispos. 1983 Mar-Apr;11(2):137-42.
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Oral phenytoin pharmacokinetics during omeprazole therapy.奥美拉唑治疗期间苯妥英钠的口服药代动力学。
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The mechanism of action of omeprazole--a survey of its inhibitory actions in vitro.奥美拉唑的作用机制——对其体外抑制作用的综述
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J Clin Invest. 1989 Feb;83(2):688-97. doi: 10.1172/JCI113933.
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Effect of omeprazole and cimetidine on plasma diazepam levels.
Eur J Clin Pharmacol. 1990;39(1):51-4. doi: 10.1007/BF02657057.
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