Drew P J, Titley O G
West Midlands Regional Plastic and Jaw Surgery Unit, Wordsley Hospital, Stourbridge.
Br J Clin Pract. 1995 Nov-Dec;49(6):297-300.
A prospective study undertaken to examine bacterial contamination at presentation, frequency and type of antibiotic prescribed, and outcome, in 50 patients presenting with hand injuries of varying severity, is reported. Results of a national survey of trends in antibiotic prescribing for similar wounds in plastic surgery units are also recorded. Preoperative swabs cultured normal flora or no growth. Forty-eight patients received antibiotics with little consistency in the agent used, route of administration, or length of treatment. Clinical wound infection occurred in three crush injuries. No significant difference in the numbers of surgeons using antibiotics for clean and crushed injuries of all types was demonstrated. The state of the wound, rather than the tissue damaged, seemed to dictate antibiotic use. In dirty wounds, however, damage to deep structures appeared to be an indication for antibiotics--significantly fewer respondents treated dirty injuries of the skin alone. The authors believe that antibiotic use in open hand injury is of no proven benefit, and that this aspect of hand surgery requires further investigation.
本文报告了一项前瞻性研究,该研究对50例不同严重程度手部损伤患者的就诊时细菌污染情况、抗生素处方的频率和类型以及治疗结果进行了检查。同时记录了一项关于整形外科单位类似伤口抗生素处方趋势的全国性调查结果。术前拭子培养出正常菌群或无细菌生长。48例患者接受了抗生素治疗,所用药物、给药途径或治疗时长缺乏一致性。3例挤压伤发生了临床伤口感染。在各类清洁伤和挤压伤中,使用抗生素的外科医生数量无显著差异。似乎决定抗生素使用的是伤口状况,而非受损组织。然而,在污染伤口中,深部结构受损似乎是使用抗生素的指征——仅治疗单纯皮肤污染伤的受访者明显较少。作者认为,开放性手部损伤使用抗生素并无已证实的益处,手部手术的这一方面需要进一步研究。