Katayama I, Yokozeki H, Nishioka K
Department of Dermatology, Tokyo Medical and Dental University School of Medicine, Japan.
Br J Dermatol. 1995 Nov;133(5):716-20. doi: 10.1111/j.1365-2133.1995.tb02744.x.
To examine the prevalence of hypohidrosis and to quantitate sweating as an exocrinopathy in Sjögren's syndrome (SS), 49 patients with SS (primary form, 38; secondary form, 11) were studied. Sweating was induced by mental stimulation such as deep breathing or hand grasping. Statistically significant reductions of sweat volume were seen in SS (P < 0.005). Patients under 50 years old showed impaired sweat function compared with normal controls (P < 0.0005). In a control study, only haemodialysis patients showed impairment of sweating and this was greater than in patients with SS aged under 50 years. These results suggest that patients with SS develop impaired sweating as an exocrine manifestation in addition to the known symptoms of xerostomia and xerophthalmus.
为了研究少汗症的患病率，并将出汗作为干燥综合征（SS）的一种外分泌腺病进行定量分析，我们对49例SS患者（原发性38例；继发性11例）进行了研究。通过深呼吸或抓握等精神刺激诱导出汗。SS患者的汗液分泌量有统计学意义的降低（P < 0.005）。50岁以下的患者与正常对照组相比，汗液功能受损（P < 0.0005）。在一项对照研究中，只有血液透析患者出汗功能受损，且这种损害大于50岁以下的SS患者。这些结果表明，SS患者除了有口干和眼干等已知症状外，还会出现出汗功能受损这一外分泌腺表现。
