• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Prostaglandin synthase 2.

作者信息

Herschman H R

机构信息

Department of Biological Chemistry, UCLA 90095, USA.

出版信息

Biochim Biophys Acta. 1996 Jan 5;1299(1):125-40. doi: 10.1016/0005-2760(95)00194-8.

DOI:10.1016/0005-2760(95)00194-8
PMID:8555245
Abstract
摘要

相似文献

1
Prostaglandin synthase 2.前列腺素合成酶2
Biochim Biophys Acta. 1996 Jan 5;1299(1):125-40. doi: 10.1016/0005-2760(95)00194-8.
2
Eicosanoids and iso-eicosanoids: constitutive, inducible and transcellular biosynthesis in vascular disease.类二十烷酸和异类二十烷酸：血管疾病中的组成性、诱导性和跨细胞生物合成
Thromb Haemost. 1998 Apr;79(4):691-705.
3
The heterologous expression and characterization of human prostaglandin G/H synthase-2 (COX-2).人前列腺素G/H合酶-2（COX-2）的异源表达与特性分析
Biochem Biophys Res Commun. 1994 May 30;201(1):356-62. doi: 10.1006/bbrc.1994.1709.
4
Bases for a spinal analgesic action of cyclooxygenase inhibitors.
Proc West Pharmacol Soc. 2002;45:225-7.
5
Formation of cyclooxygenase-derived eicosanoids by a parasitic intravascular nematode.一种寄生性血管内线虫生成环氧化酶衍生的类花生酸。
Adv Prostaglandin Thromboxane Leukot Res. 1991;21B:509-12.
6
Differential regulation of prostaglandin E2 and thromboxane A2 production in human monocytes: implications for the use of cyclooxygenase inhibitors.人单核细胞中前列腺素E2和血栓素A2生成的差异调节：对环氧化酶抑制剂应用的启示
J Immunol. 2000 Aug 1;165(3):1605-11. doi: 10.4049/jimmunol.165.3.1605.
7
[Physiopathological and therapeutic study of collagen diseases based on results of clinical tests--role of prostaglandins].基于临床试验结果的胶原病生理病理学与治疗研究——前列腺素的作用
Nihon Naika Gakkai Zasshi. 1998 Dec 10;87(12):2438-45.
8
Prostaglandin H synthase as a limiting enzyme of prostaglandin synthesis: substrate-induced inactivation as a new kind of enzyme activity regulation.
Biotechnol Appl Biochem. 1993 Jun;17(3):291-304.
9
Roles of cyclooxygenase (COX)-1 and COX-2 in prostanoid production by human endothelial cells: selective up-regulation of prostacyclin synthesis by COX-2.环氧化酶（COX）-1和COX-2在人内皮细胞前列腺素生成中的作用：COX-2对前列环素合成的选择性上调。
J Immunol. 2001 Sep 1;167(5):2831-8. doi: 10.4049/jimmunol.167.5.2831.
10
[The yin yang of inflammation: inducible and constitutive cyclooxygenase. Nimesulide and selective inhibitors of inducible cyclooxygenase].
Eur Rev Med Pharmacol Sci. 1998 May-Jun;2(3 Suppl 1):1-8.

引用本文的文献

1
Biological Activities of Etodolac-Based Hydrazone, Thiazolidinone and Triazole Derivatives on Breast Cancer Cell Lines MCF-7 and MDA-MB-231.依托度酸基腙、噻唑烷酮和三唑衍生物对乳腺癌细胞系MCF-7和MDA-MB-231的生物活性
J Biochem Mol Toxicol. 2025 Aug;39(8):e70428. doi: 10.1002/jbt.70428.
2
COX-2 in lung cancer: Mechanisms, development, and targeted therapies.肺癌中的COX-2：机制、进展及靶向治疗
Chronic Dis Transl Med. 2024 Mar 12;10(4):281-292. doi: 10.1002/cdt3.120. eCollection 2024 Dec.
3
Polyunsaturated Fatty Acids as Potential Treatments for COVID-19-Induced Anosmia.
多不饱和脂肪酸作为新冠病毒感染所致嗅觉丧失的潜在治疗方法
Biomedicines. 2024 Sep 12;12(9):2085. doi: 10.3390/biomedicines12092085.
4
Synthesis and elucidation of strained galactopyronose esters as selective cyclooxygenase-2 inhibitor: a comprehensive computational approach.作为选择性环氧合酶-2抑制剂的应变吡喃半乳糖酯的合成与阐释：一种综合计算方法
RSC Adv. 2024 Sep 24;14(41):30469-30481. doi: 10.1039/d4ra03520h. eCollection 2024 Sep 18.
5
Unlocking the combined action of L. essential oil and Thym honey: pharmacological activities, molecular docking, and anti-inflammatory effect.揭示罗勒精油与百里香蜂蜜的联合作用：药理活性、分子对接及抗炎作用
Heliyon. 2024 May 28;10(11):e31922. doi: 10.1016/j.heliyon.2024.e31922. eCollection 2024 Jun 15.
6
Arachidonic acid-derived lipid mediators in multiple sclerosis pathogenesis: fueling or dampening disease progression?花生四烯酸衍生的脂质介质在多发性硬化症发病机制中的作用：促进还是抑制疾病进展？
J Neuroinflammation. 2024 Jan 17;21(1):21. doi: 10.1186/s12974-023-02981-w.
7
Himalayan flora: targeting various molecular pathways in lung cancer.喜马拉雅地区的植物群：针对肺癌中的多种分子途径。
Med Oncol. 2023 Oct 3;40(11):314. doi: 10.1007/s12032-023-02171-x.
8
PGE2 Produced by Exogenous MSCs Promotes Immunoregulation in ARDS Induced by Highly Pathogenic Influenza A through Activation of the Wnt-β-Catenin Signaling Pathway.外源性间充质干细胞产生的 PGE2 通过激活 Wnt-β-连环蛋白信号通路促进高致病性甲型流感诱导的 ARDS 的免疫调节。
Int J Mol Sci. 2023 Apr 14;24(8):7299. doi: 10.3390/ijms24087299.
9
Design, synthesis, and biological evaluation of new 2-(4-(methylsulfonyl)phenyl)--phenylimidazo[1,2-]pyridin-3-amine as selective COX-2 inhibitors.新型2-(4-(甲基磺酰基)苯基)-苯基咪唑并[1,2 - ]吡啶-3-胺作为选择性COX-2抑制剂的设计、合成及生物学评价
Med Chem Res. 2023;32(5):856-868. doi: 10.1007/s00044-023-03041-x. Epub 2023 Mar 2.
10
Irigenin, a novel lead from Iris confusa for management of Helicobacter pylori infection with selective COX-2 and HpIMPDH inhibitory potential.鸢尾苷元，一种新型的鸢尾属先导化合物，具有选择性 COX-2 和 HpIMPDH 抑制潜力，可用于幽门螺杆菌感染的治疗。
Sci Rep. 2022 Jul 6;12(1):11457. doi: 10.1038/s41598-022-15361-w.