Dobbertein P, Muenster H
Finnigan MAT, Bremen, Germany.
J Chromatogr A. 1995 Sep 29;712(1):3-15. doi: 10.1016/0021-9673(95)00330-p.
In three application examples we demonstrate how the capabilities of a modern atmospheric pressure ionization (API) source, as a universal LC-MS coupling tool, are supplemented by the high mass resolution available on double focusing sector instruments. The examples include charge state determination in complex electrospray ionization-collisional induced dissociation (ESI-CID) spectra of multiply charged ions, mixture analysis of multicomponent samples without prior chromatographic separation, and very sensitive and highly specific detection of pesticides using atmospheric pressure chemical ionization (APCI).