Roos D, Willanger R
Acta Neurol Scand. 1977 May;55(5):363-76. doi: 10.1111/j.1600-0404.1977.tb05655.x.
Forty-two gastrectomized patients (mean age 56 years) with a serum B12 level less than 200 pg/ml were studied by psychological testing and electroencephalography. A total of 50 per cent exhibited mild to moderate or more severe intellectual impairment, judging by the history and psychological testing. EEG abnormalities were found, mainly in the form of reduced dominant activity, in 48 per cent. The results of psychological testing were in accurate conformity with the findings of dementia due to other reasons. The characteristic findings were depression and lability of affect, with a high frequency of suicidal attempts (20 per cent). We interpret the cerebral abnormalities as a result of vitamin B12 deficiency.
对42例血清维生素B12水平低于200 pg/ml的胃切除患者（平均年龄56岁）进行了心理测试和脑电图检查。根据病史和心理测试判断，共有50%的患者表现出轻度至中度或更严重的智力障碍。48%的患者发现脑电图异常，主要表现为优势活动减少。心理测试结果与其他原因导致的痴呆症结果完全相符。特征性表现为抑郁和情感不稳定，自杀未遂发生率较高（20%）。我们将脑部异常解释为维生素B12缺乏的结果。
