[Sézary syndrome. A case report].

This paper describes a patient who exhibits all signs of Sézary-syndrome. During the 15 years of sickness, the patient has developed a generalised erythrodermia, skin infiltrations, hyperkeratosis on the palms and the foot soles, changes in pigmentation, and generalised swelling of the lymph nodes. Two modifications of Sézary's cells have been found in the peripheral blood and the specific skin infiltrations by both light and electron microscopy. The serum contains large amounts of a macrophage migration inhibitory factor. The illness does not respond to chemotherapy.