Jambhekar N A, Borges A M
Department of Pathology, Tata Memorial Hospital, Parel, Bombay, India.
Indian J Cancer. 1994 Sep;31(3):207-11.
Melanomas are known to show a wide range of morphological expression. Desmoplastic Malignant Melanoma (DMM) which is a variant of spindle cell melanoma, is often characterised by conspicuous growth in and around nerves which leads to a mistaken diagnosis of malignant Peripheral Nerve Sheath tumours (MPNST). We report two such cases of spindle celled DMM of the foot which displayed neurotropism. The problems and the clinical relevance of distinguishing this variant of melanoma from MPNST is discussed.
众所周知，黑色素瘤呈现出广泛的形态学表现。促纤维增生性恶性黑色素瘤（DMM）是梭形细胞黑色素瘤的一种变体，其特征通常是在神经内外显著生长，这会导致误诊为恶性外周神经鞘瘤（MPNST）。我们报告了两例足部梭形细胞DMM病例，它们表现出嗜神经性。本文讨论了将这种黑色素瘤变体与MPNST区分开来的问题及临床意义。
