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伴有IgM水平升高和中性粒细胞减少的免疫缺陷患者中的食管溃疡。

Esophageal ulcers in immunodeficiency with elevated levels of IgM and neutropenia.

作者信息

Vanderhoof J A, Rich K C, Stiehm E R, Ament M E

出版信息

Am J Dis Child. 1977 May;131(5):551-2. doi: 10.1001/archpedi.1977.02120180065010.

Abstract

A 17-year-old boy with immunodeficiency, elevated levels of IgM,and neutropenia developed distal esophageal ulcers and stricture. Although his lower esophageal sphincter pressure was decreased, he had normal acid reflux test results, normal findings from acid clearing studies, and absence of diffuse esophagitis at esophagoscopy. Neutropenia and hypogammaglobulinemia are postulated as pathogenic factors in his esophageal ulcers.

摘要

一名17岁免疫缺陷、IgM水平升高且患有中性粒细胞减少症的男孩出现了食管远端溃疡和狭窄。尽管他的食管下括约肌压力降低,但他的酸反流试验结果正常,酸清除研究结果正常,且食管镜检查未发现弥漫性食管炎。中性粒细胞减少症和低丙种球蛋白血症被认为是其食管溃疡的致病因素。

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IgA deficiency and neutropenia.免疫球蛋白A缺乏症与中性粒细胞减少症。
Br Med J. 1976 Mar 6;1(6009):563. doi: 10.1136/bmj.1.6009.563.

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