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老年女性I型压力性尿失禁的内镜下胶原注射治疗

Endoscopic collagen injection therapy in elderly women with type I stress urinary incontinence.

作者信息

Faerber G J

机构信息

Section of Urology, University of Michigan Medical Center, Veteran's Administration Medical Center, Ann Arbor, USA.

出版信息

J Urol. 1996 Feb;155(2):512-4.

PMID:8558648
Abstract

PURPOSE

The safety and efficacy of collagen injection therapy for the treatment of type I stress urinary incontinence were determined.

MATERIALS AND METHODS

A total of 12 women 68 to 85 years old (mean age 76) with type I stress urinary incontinence underwent collagen injection. Incontinence was subjectively categorized as grades 0 to 3, and Valsalva leak point pressures were measured before and after injection.

RESULTS

At a mean of 10.3 months (range 3 to 24) 10 of the 12 women (83%) were cured, while the remaining 2 noticed subjective improvement in incontinence. Average number of injections per patient was 1.25 (1 injection in 9 and 2 in 3), average total collagen injected per patient was 2.2 cc (range 1.0 to 3.5) and average increase in Valsalva leak point pressure after collagen injection was 22 cm. water (range 0 to 40).

CONCLUSIONS

Collagen injection appears to be an effective alternative method for the treatment of type I stress urinary incontinence in elderly women.

摘要

目的

确定胶原蛋白注射疗法治疗Ⅰ型压力性尿失禁的安全性和有效性。

材料与方法

12名年龄在68至85岁(平均年龄76岁)的Ⅰ型压力性尿失禁女性接受了胶原蛋白注射。尿失禁主观分为0至3级,并在注射前后测量瓦尔萨尔瓦漏尿点压力。

结果

平均10.3个月(范围3至24个月)时,12名女性中有10名(83%)治愈,其余2名尿失禁有主观改善。每位患者平均注射次数为1.25次(9名患者注射1次,3名患者注射2次),每位患者平均注射的胶原蛋白总量为2.2立方厘米(范围1.0至3.5),胶原蛋白注射后瓦尔萨尔瓦漏尿点压力平均增加22厘米水柱(范围0至40)。

结论

胶原蛋白注射似乎是治疗老年女性Ⅰ型压力性尿失禁的一种有效替代方法。

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