Klutke C G, Nadler R B, Tiemann D, Andriole G L
Division of Urologic Surgery, Washington University School of Medicine, St. Louis, Missouri, USA.
J Urol. 1996 Nov;156(5):1703-6.
Results of retrograde transurethral collagen injection for treatment of stress urinary incontinence have been generally disappointing for men with intrinsic sphincter deficiency following radical prostatectomy. We describe a new technique of antegrade transvesical collagen injection using suprapublic percutaneous bladder access.
Between October 1994 and January 1996, 20 patients underwent antegrade collagen injection for post-radical prostatectomy stress urinary incontinence. Evaluation by pad test, urodynamics and subjective scores was performed before and after injection.
At a mean followup of 8.5 months 9 of 20 patients (45%) had significant subjective improvement and 5 (25%) were totally dry.
Antegrade collagen injection is a promising and simple method of correcting post-radical prostatectomy stress urinary incontinence. Further study and longer followup are necessary to determine its precise role in the treatment of this condition.
对于根治性前列腺切除术后存在内在括约肌功能缺陷的男性患者，逆行经尿道胶原注射治疗压力性尿失禁的结果总体令人失望。我们描述一种经耻骨上经皮膀胱穿刺进行顺行膀胱内胶原注射的新技术。
1994年10月至1996年1月，20例患者接受了根治性前列腺切除术后压力性尿失禁的顺行胶原注射治疗。在注射前后通过尿垫试验、尿动力学检查和主观评分进行评估。
平均随访8.5个月时，20例患者中有9例（45%）主观症状有显著改善，5例（25%）完全无尿失禁。
顺行胶原注射是一种有前景且简单的纠正根治性前列腺切除术后压力性尿失禁的方法。需要进一步研究和更长时间的随访以确定其在治疗这种疾病中的精确作用。
