Kendrick J S, Tierney E F, Lawson H W, Strauss L T, Klein L, Atrash H K
Division of Reproductive Health, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Obstet Gynecol. 1996 Feb;87(2):297-301. doi: 10.1016/0029-7844(95)00392-4.
To determine whether previous cesarean delivery is an independent risk factor for ectopic pregnancy.
We analyzed data collected between October 1988 and August 1990 from a case-control study of ectopic pregnancy among parous, black, non-Hispanic women, 18-44 years old, at a major metropolitan hospital in Georgia. Cases were 138 women with confirmed ectopic pregnancy; controls were 842 women either seeking abortion or delivering an infant. Unconditional logistic regression was used to estimate the relative risk while controlling for the effects of potential confounders selected a priori.
Adjusted for age, parity, marital status, history of pelvic inflammatory disease, infertility, douching, and smoking, the odds ratio was 0.6 (95% confidence interval 0.4-1.1), indicating no significant association.
We found no evidence of an increased risk of ectopic pregnancy related to previous cesarean delivery.
确定既往剖宫产是否为异位妊娠的独立危险因素。
我们分析了1988年10月至1990年8月间在佐治亚州一家大型都市医院对18 - 44岁已生育、黑人、非西班牙裔妇女进行的异位妊娠病例对照研究中收集的数据。病例为138例确诊异位妊娠的妇女；对照为842例寻求堕胎或分娩婴儿的妇女。在控制先验选择的潜在混杂因素影响的同时，使用无条件逻辑回归来估计相对风险。
在调整了年龄、产次、婚姻状况、盆腔炎病史、不孕、冲洗和吸烟因素后，比值比为0.6（95%置信区间0.4 - 1.1），表明无显著关联。
我们没有发现与既往剖宫产相关的异位妊娠风险增加的证据。
