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[多灶性骨结核:附病例报告]

[Multifocal bone tuberculosis: apropos of a case].

作者信息

Moujtahid M, Essadki B, Lamine A, Bennouna D, Zryouil B

机构信息

Service de Traumatologie-Orthopédie (Aile 4), CHU Ibn Rochd, Casablanca, Maroc.

出版信息

Rev Chir Orthop Reparatrice Appar Mot. 1995;81(6):553-6.

PMID:8560027
Abstract

INTRODUCTION

Tuberculosis of bone is rare (10 to 20 per cent of all skeletal tuberculosis). The multifocal form is exceptional even in endemic countries of tuberculosis. It constitutes less than 5 per cent of all osseous tuberculosis.

CASE REPORT

O.H. 34 year-old, Moroccan woman of black race not vaccinated against tuberculosis, with a contagion, complained for a year from scapular pain and weight loss. She noticed that two masses had appeared six months ago. The patient was feverish (38 degrees). The physical exam showed a non inflammatory mass 10 cm wide located in front of the left sacroiliac joint and seeming to be a cold abscess. The radiologic assessment showed a lytic image of the humerus upper extremity, the right iliopubis branch, the left ischium and the left iliac wing. The surgical biopsy of the humerus showed an evolutive caseo-follicular tuberculosis. The nuclear scan of bone found two other localizations in the fourth lumbar vertebra and the ninth left rib. We concluded to a multifocal bone tuberculosis with seven localizations: The upper extremity of both humerus Right pubis Left ischium Left iliac wing 4th lumbar vertebra 9th left rib. The treatment consisted in a specific antibiotic therapy for 6 months associated to the evacuation of the cold abscess.

DISCUSSION

Multifocal bone tuberculosis is more frequent in young adults of black race. The beginning of the disease is progressive and the fistulas are the main reason of consultation. The radiologic lesions are not specific and have a geodic shape rimmed with an osteocondensation. Multifocal bone tuberculosis in black african predominate in flat bones. Otherwise in the white race it is located in the long bones extremities. The diagnosis of certitude is based on histologic findings of the peripheric bone lesion. The specific antibiotic therapy leads to the recovery if given early. Short protocols (9 or 6 months) are recently more used with success.

摘要

引言

骨结核较为罕见(占所有骨结核的10%至20%)。即便在结核病流行国家,多灶性骨结核也很罕见。它占所有骨结核的比例不到5%。

病例报告

O.H.,一名34岁未接种过结核病疫苗的摩洛哥黑人女性,有接触史,因肩胛疼痛和体重减轻已持续一年。她注意到六个月前出现了两个肿块。患者发热(38度)。体格检查显示,左骶髂关节前方有一个10厘米宽的非炎性肿块,似乎是一个寒性脓肿。影像学评估显示肱骨上端、右耻骨支、左坐骨和左髂骨翼有溶骨性影像。肱骨手术活检显示为进展期干酪滤泡性结核。骨核素扫描在第四腰椎和左第九肋骨发现另外两个病灶。我们诊断为多灶性骨结核,共有七个病灶部位:双侧肱骨上端、右耻骨、左坐骨、左髂骨翼、第四腰椎、左第九肋骨。治疗包括为期6个月的特异性抗生素治疗以及寒性脓肿引流。

讨论

多灶性骨结核在黑人青年中更为常见。疾病起病隐匿,瘘管是就诊的主要原因。影像学病变不具特异性,呈地图状,周边有骨质增生。非洲黑人的多灶性骨结核主要发生在扁骨。而在白种人中,多发生于长骨末端。确诊诊断基于外周骨病变的组织学检查结果。早期给予特异性抗生素治疗可实现康复。近期,9个月或6个月的短疗程治疗方案应用更为成功。

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