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儿童院外心脏骤停——流行病学与结局

Paediatric out-of-hospital cardiac arrests--epidemiology and outcome.

作者信息

Kuisma M, Suominen P, Korpela R

机构信息

Laakariyksikko, Helsinki Rescue Department, Department of Health, Finland.

出版信息

Resuscitation. 1995 Oct;30(2):141-50. doi: 10.1016/0300-9572(95)00888-z.

Abstract

OBJECTIVE

To determine the epidemiology and aetiology of out-of-hospital paediatric cardiac arrest and the outcome of resuscitation and to apply the Utstein template for the paediatric cardiac arrest population.

DESIGN

Retrospective cohort study.

SETTING

A middle-sized urban city (population 516,000) served by a single emergency medical services (EMS) system.

PATIENTS

79 consecutive paediatric (age under 16 years) prehospital cardiac arrest patients between January 1, 1985 and December 31, 1994. No patient was excluded.

INTERVENTION

Advanced paediatric life support according to the recommendations of American Heart Association.

MAIN OUTCOME MEASURES

Survival from cardiac arrest to discharge and factors associated with favourable outcome defined as alive 1 year after discharge with Bloom category I or II.

RESULTS

79 patients had cardiac arrest. The incidence of paediatric out-of-hospital cardiac arrest and sudden unexpected out-of-hospital death was 9.8 and 8.9/100,000/inhabitants aged under 16, respectively. The mean age was 2.9 years, 72.2% were under 18 months. SIDS was the leading cause of cardiac arrest followed by trauma, airway related cardiac arrest and (near)drowning. Fifty-two patients were considered for resuscitation in whom asystole was the most common initial rhythm (78.9%) followed by pulseless electrical activity (13.5%) and ventricular fibrillation (3.8%). Resuscitation was attempted in 34 patients. The overall survival rate was 9.6%, for attempted resuscitation 14.7%, for attempted resuscitation when cardiac arrest was witnessed 25.0% and for attempted resuscitation with witnessed arrest of cardiac origin 0%. Favourable outcome was registered in four of five survivors. Factors associated with favourable outcome were collapse in a public place, the near-drowning aetiology of arrest, bystander initiated CPR and short duration of resuscitation. Multivariate regression analysis showed no factor related to favourable outcome, but MICU time interval < 10 min was related with survival. Due to the retrospective nature of this study all core times could not be obtained. In spite of this, the Utstein template was applicable also in our paediatric cardiac arrest population.

CONCLUSIONS

Survival from paediatric cardiac arrest has remained low. The overall survival rate was 9.6%, survival after attempted resuscitation 14.7% and 0% when resuscitation was attempted in witnessed arrest of cardiac origin. Asystole was the most common initial rhythm and the four leading causes for cardiac arrest were SIDS, trauma, airway related arrest and (near)drowning. The Utstein template adopted for adult out-of-hospital cardiac arrests was was found applicable also in paediatric cardiac arrests.

摘要

目的

确定院外小儿心脏骤停的流行病学、病因及复苏结局,并将Utstein模板应用于小儿心脏骤停人群。

设计

回顾性队列研究。

地点

由单一紧急医疗服务(EMS)系统服务的中型城市(人口516,000)。

患者

1985年1月1日至1994年12月31日期间连续79例院前小儿(16岁以下)心脏骤停患者。无患者被排除。

干预

根据美国心脏协会的建议进行高级小儿生命支持。

主要结局指标

心脏骤停后存活至出院以及与良好结局相关的因素,良好结局定义为出院后1年存活且Bloom分类为I或II级。

结果

79例患者发生心脏骤停。16岁以下儿童院外心脏骤停和院外意外猝死的发生率分别为9.8/10万居民和8.9/10万居民。平均年龄为2.9岁,72.2%的患者年龄在18个月以下。婴儿猝死综合征是心脏骤停的主要原因,其次是创伤、气道相关心脏骤停和(近)溺水。52例患者被考虑进行复苏,其中心脏停搏是最常见的初始心律(78.9%),其次是无脉电活动(13.5%)和心室颤动(3.8%)。34例患者尝试进行了复苏。总体存活率为9.6%,尝试复苏的患者为14.7%,目睹心脏骤停时尝试复苏的患者为25.0%,目睹心脏源性骤停时尝试复苏的患者为0%。五名幸存者中有四名获得了良好结局。与良好结局相关的因素包括在公共场所发生心脏骤停、心脏骤停的近溺水病因、旁观者实施心肺复苏以及复苏持续时间短。多因素回归分析显示无因素与良好结局相关,但重症监护病房时间间隔<10分钟与存活相关。由于本研究的回顾性性质,无法获得所有核心时间。尽管如此,Utstein模板也适用于我们的小儿心脏骤停人群。

结论

小儿心脏骤停后的存活率仍然很低。总体存活率为9.6%,尝试复苏后的存活率为14.7%,目睹心脏源性骤停时尝试复苏的存活率为0%。心脏停搏是最常见的初始心律,心脏骤停的四个主要原因是婴儿猝死综合征、创伤、气道相关骤停和(近)溺水。发现用于成人院外心脏骤停的Utstein模板也适用于小儿心脏骤停。

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