Brentani R R, Brentani M M
Department of Oncologic and Radiologic, University of São Paulo.
Rev Hosp Clin Fac Med Sao Paulo. 1995 Jul-Aug;50(4):240-2.
Oncogene amplification and loss of heterozygosity for tumor suppressor genes have been correlated with prognosis in a variety of human tumors. Detection of mutations in tumor suppressor genes have been found to serve as risk factor determinants in gastrointestinal adenocarcinomas.