Norcia A M, Hamer R D, Jampolsky A, Orel-Bixler D
Smith-Kettlewell Eye Research Institute, San Francisco, CA 94115, USA.
Vision Res. 1995 Dec;35(23-24):3279-96. doi: 10.1016/0042-6989(95)00144-4.
Monocular oscillatory-motion visual evoked potentials (VEPs) were measured in prospective and retrospective groups of infantile esotropia patients who had been aligned surgically at different ages. A nasalward-temporal response bias that is present prior to surgery was reduced below pre-surgery levels in the prospective group. Patients in the retrospective group who had been aligned before 2 yr of age showed lower levels of response asymmetry than those who were aligned after age 2. The data imply that binocular motion processing mechanisms in infantile esotropia patients are capable of some degree of recovery, and that this plasticity is restricted to a critical period of visual development.
