Marković S, Kronja G, Odavić M, Sćekić M, Perovanović M
Vojnomedicinska akademija, Institut za nuklearnu medicinu, Klinika za opstu i vaskularnu hirurgiju, Beograd.
Vojnosanit Pregl. 1994 May-Jun;51(3):208-13.
In 50 patients aged 60 +/- 4 operated for colorectal carcinoma simultaneous combined radionuclide phlebography (RNP) and pulmonary perfusion scintigraphy (PPS) using 99Tcm labeled macroaggregates of the human serum albumin (MAHSA) were performed within 20 postoperative days aiming to detect deep vein thrombosis (DVT) and pulmonary thromboembolism (PTE). The aim of the study was to determine the incidence and segmental DVT localization as well as incidence, localization and clinical characteristics of developed pulmonary perfusion disorders. Deep vein thrombosis was detected in 33 (66%) patients with rather uniform distribution in vein segments. According to their scintigraphic characteristics the findings suggested recent thrombosis in almost all cases (only two of them had signs of chronic thrombosis). Of patients with detected DVT 17 (52%) had pulmonary perfusion disorders of which 10 (59%) were unilateral (7 right and 3 left) and 7 (42%) bilateral. Characteristics and extent of perfusion defects suggested very probable PTE in 11 (65%) patients and less probable in 6 (35%). It has been concluded that patients operated for colorectal carcinoma were highly exposed to DVT and PTE development which necessitates all measures contributing to their prevention.
对50例年龄在60±4岁、因结直肠癌接受手术的患者，在术后20天内同时进行了放射性核素静脉造影（RNP）和肺灌注闪烁扫描（PPS），使用99锝标记的人血清白蛋白大聚合体（MAHSA），目的是检测深静脉血栓形成（DVT）和肺血栓栓塞（PTE）。本研究的目的是确定DVT的发生率和节段性定位，以及所发生的肺灌注障碍的发生率、定位和临床特征。在33例（66%）患者中检测到深静脉血栓形成，在静脉段分布较为均匀。根据闪烁扫描特征，几乎所有病例的检查结果提示为近期血栓形成（其中只有2例有慢性血栓形成的迹象）。在检测到DVT的患者中，17例（52%）有肺灌注障碍，其中10例（59%）为单侧（7例右侧，3例左侧），7例（42%）为双侧。灌注缺损的特征和范围表明，11例（65%）患者极有可能发生PTE，6例（35%）可能性较小。得出的结论是，因结直肠癌接受手术的患者极易发生DVT和PTE，这就需要采取一切有助于预防的措施。
