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[根治性手术治疗直肠癌盆腔复发成像的新概念——核磁共振断层扫描与抗癌胚抗原免疫闪烁成像(单光子发射计算机断层扫描)的图像融合:技术与临床实例]

[A new concept in imaging pelvic recurrence of curatively operated rectal carcinoma--image fusion of nuclear magnetic resonance tomography and anti-CEA immunoscintigraphy (SPECT): technique and clinical example].

作者信息

Kronberger L, Fueger G F, Nicoletti R, Ranner G, Wiltgen M, Stollberger R, Graif E, Uranüs S, Hauser H, Mischinger H J

机构信息

Klinische Abteilung für Allgemeinchirurgie, Universitätsklinik für Chirurgie, Graz.

出版信息

Wien Klin Wochenschr. 1995;107(23):710-3.

PMID:8560891
Abstract

We present a new technique of image fusion (IF) of magnetic resonance imaging (MRT) and anti-CEA-immunoscintigraphy (Behring 431/26) and single photon emission computed tomography (SPECT). We performed SPECT and MRT within 8 hours on the same day. Glucagon intravenously was used to reduce artefacts due to intestinal motility. Before image fusion we analysed the SPECT and MRT images independently of each other. The MRT and SPECT were connected by a local area network (LAN) to a Gateway computer, which is also used as a picture archive. There a program automatically starts, translates the MRT data from the ACR/NEMA format to the Elscint one and these data are sent for image fusion to the nuclear medicine computer Elscint SP1. By means of a clinical example we present anatomic concordant superimposition and explain the findings and the clinical value of our technique. This system and technique are equally applicable to other digital imaging investigations. By IF, on the basis of the certain evidence of the tracer depot of a pathological lesion diagnosed by MRT and the reliability of the anatomical assignment of a focal lesion diagnosed by SPECT, early detection of local recurrence after surgical treatment of rectal cancer, the correct localisation of recurrent disease and its distinction from non-malignant tissue becomes possible. This enables planning of further therapeutical strategies.

摘要

我们展示了一种磁共振成像(MRT)与抗癌胚抗原免疫闪烁显像(贝林431/26)及单光子发射计算机断层扫描(SPECT)的图像融合(IF)新技术。我们在同一天8小时内完成了SPECT和MRT检查。静脉注射胰高血糖素以减少肠道蠕动引起的伪影。在进行图像融合之前,我们分别独立分析了SPECT和MRT图像。MRT和SPECT通过局域网(LAN)连接到一台网关计算机,该计算机也用作图像存档。在那里,一个程序会自动启动,将MRT数据从ACR/NEMA格式转换为埃尔辛特格式,然后将这些数据发送到核医学计算机埃尔辛特SP1进行图像融合。通过一个临床实例,我们展示了解剖学上的一致叠加,并解释了我们技术的发现和临床价值。该系统和技术同样适用于其他数字成像检查。通过图像融合,基于MRT诊断的病理性病变示踪剂储存库的某些证据以及SPECT诊断的局灶性病变解剖定位的可靠性,直肠癌手术治疗后局部复发的早期检测、复发性疾病的正确定位及其与非恶性组织的区分成为可能。这有助于规划进一步的治疗策略。

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