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[高压氧手术及氧疗在梭菌性肌坏死中的应用]

[Hyperbaric surgery and oxygen therapy in clostridial myonecrosis].

作者信息

Smolle-Jüttner F M, Pinter H, Neuhold K H, Feierl G, Sixl T, Ratzenhofer B, Kovac H, Friehs G

机构信息

Klinische Abteilung für Thorax-und hyperbare Chirurgie, Chirurgischen Universitätsklinik, Universität Graz.

出版信息

Wien Klin Wochenschr. 1995;107(23):739-41.

PMID:8560898
Abstract

116 patients with verified clostridial myonecrosis were treated by means of a regimen of combined cyclic hyperbaric oxygenation at 3 ata and repeated necrectomy. With proximal localization of gas gangrene in the elbow or knee (n = 55) 34.5% of patients survived, whilst with peripheral localization at the limbs (n = 44) the survival rate was 88.6% amputation being avoided in 21 of these cases. Abdominal localization (n = 17) was associated with the lowest survival rate (23.5%). In spite of severe clostridial toxicity in 80.1% of patients at the time of admission, the overall mortality was 50.8%.

摘要

116例经证实患有梭菌性肌坏死的患者采用3个绝对大气压的联合循环高压氧疗方案并重复进行坏死组织切除术进行治疗。气性坏疽发生在肘部或膝部近端(n = 55)时,34.5%的患者存活;而发生在四肢外周(n = 44)时,存活率为88.6%,其中21例避免了截肢。腹部发病(n = 17)的存活率最低(23.5%)。尽管80.1%的患者入院时存在严重的梭菌毒性,但总死亡率为50.8%。

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