远端胃切除术后胃食管反流与胃排空之间的关系。

Relationship between gastroesophageal reflux and gastric emptying after distal gastrectomy.

作者信息

Fujiwara Y, Nakagawa K, Tanaka T, Utsunomiya J

机构信息

Second Department of Surgery, Hyogo College of Medicine, Japan.

出版信息

Am J Gastroenterol. 1996 Jan;91(1):75-9.

PMID:8561148

Abstract

OBJECTIVES

Our objective was to determine whether delayed gastric emptying contributes to gastroesophageal reflux after distal gastrectomy.

METHODS

To study gastric emptying and gastroesophageal reflux, we used a tecnnetium-labeled mixed liquid and solid test meal in 46 distal gastrectomy patients (19 with reflux symptoms and 27 without) and in 10 controls. The relationship of reflux symptoms to gastric emptying and the correlation between gastric emptying and the scintigraphic reflux index were evaluated.

RESULTS

The reflux index was significantly higher in the symptomatic group (9.76 +/- 5.64%) than in the asymptomatic group (4.45 +/- 2.70%). The gastric emptying half time was significantly longer in the symptomatic group (53.13 +/- 19.39 min) than in asymptomatic group (34.26 +/- 20.40 min) and in normal controls (27.31 +/- 4.60 min). There was a significant linear correlation between the scintigraphic reflux index and the gastric emptying half time (r = 0.505,p < 0.001).

CONCLUSIONS

These findings suggest that scintigraphy is a reasonably accurate test for detecting gastroesophageal reflux and that delayed gastric emptying plays an important role in the development of reflux after distal gastrectomy.

摘要

目的

我们的目的是确定胃排空延迟是否会导致远端胃切除术后胃食管反流。

方法

为研究胃排空和胃食管反流，我们对46例远端胃切除患者（19例有反流症状，27例无反流症状）及10名对照者使用了锝标记的混合液体和固体试验餐。评估了反流症状与胃排空的关系以及胃排空与闪烁扫描反流指数之间的相关性。

结果

有症状组的反流指数（9.76±5.64%）显著高于无症状组（4.45±2.70%）。有症状组的胃排空半衰期（53.13±19.39分钟）显著长于无症状组（34.26±20.40分钟）和正常对照组（27.31±4.60分钟）。闪烁扫描反流指数与胃排空半衰期之间存在显著的线性相关性（r = 0.505，p < 0.001）。