Krupp W F, Jans P J
Department of Neurosurgery, Alfried Krupp Hospital, Essen, Germany.
Br J Neurosurg. 1995;9(5):619-27. doi: 10.1080/02688699550040909.
Despite the high incidence of chronic subdural haematoma (SDH), to date relatively few authors have undertaken a systematic analysis of the results attained following burr-hole craniostomy and closed-system drainage on the basis of a study involving a large patient population defined according to clear-cut criteria. Between 1980 and 1993, surgery was performed on 212 patients with a chronic SDH. In a retrospective study, the condition of each patient was assessed at the time of admission on the basis of the Bender Scale and the results 4 weeks after discharge were classified according to the Glasgow Outcome Scale (GOS). At admission, 165 patients (78%) were in a satisfactory condition (Stage 1 or 2); 47 (22%) were at Stage 3 or 4, i.e. stuporous or comatose. Nine (4%) of the patients died; none of these deaths was attributable to the operation. In addition to significant extracerebral disease (2.4%), CT revealed ischaemic cerebral infarctions in three patients (1.4%) after removal of the SDH. The operative morbidity was 4.2%. In 22% of the patients, surgical intervention was required to remove a recurring SDH. In 90% of the patients, the results achieved could be graded as 'very good' or 'good' (GOS 1 or 2). The results were related to the condition at admission (p < 0.001) and the patient's age (p < 0.05). Factors that did not have a significant effect on the outcome included whether the SDH formation was bilateral or unilateral, the extent of neomembranous organization of the haematoma, and the amount of primary cerebral expansion following decompression. We were able to confirm the results of previous studies that the method used is a highly effective treatment, with a low incidence of complications.
尽管慢性硬膜下血肿(SDH)的发病率很高,但迄今为止,相对较少的作者基于一项涉及根据明确标准定义的大量患者群体的研究,对钻孔开颅术和闭式引流术后所取得的结果进行系统分析。1980年至1993年间,对212例慢性SDH患者进行了手术。在一项回顾性研究中,根据本德量表在入院时评估每位患者的病情,并根据格拉斯哥预后量表(GOS)对出院4周后的结果进行分类。入院时,165例患者(78%)病情良好(1期或2期);47例(22%)处于3期或4期,即昏睡或昏迷状态。9例(4%)患者死亡;这些死亡均与手术无关。除了严重的脑外疾病(2.4%)外,CT显示3例患者(1.4%)在清除SDH后出现缺血性脑梗死。手术发病率为4.2%。22%的患者需要手术干预以清除复发性SDH。90%的患者所取得的结果可评为“非常好”或“好”(GOS 1或2)。结果与入院时的病情(p < 0.001)和患者年龄(p < 0.05)有关。对结果没有显著影响的因素包括SDH形成是双侧还是单侧、血肿新膜组织的程度以及减压后原发性脑扩张的量。我们能够证实先前研究的结果,即所采用的方法是一种高效的治疗方法,并发症发生率低。