成人T细胞白血病临床表现为腹水和胸腔积液。

Adult T cell leukemia clinically manifested with ascites and pleural effusion.

作者信息

Saburi Y, Inage T, Ohtsuka K, Nagai T, Ishii T, Nishimiya M, Matsunaga K, Miyazaki S, Moriuchi A, Fujii H

机构信息

Division of Internal Medicine, Oita City Medical Association's Almeida Memorial Hospital.

出版信息

Intern Med. 1995 Aug;34(8):815-8. doi: 10.2169/internalmedicine.34.815.

DOI:10.2169/internalmedicine.34.815

PMID:8563129

Abstract

A 62-year-old man with adult T cell leukemia (ATL) presented with complaints of anorexia and abdominal fullness. Evaluation revealed ascites and pleural effusion, but no lymph node swelling, hepatosplenomegaly, or skin involvement. The diagnosis of ATL was made by the detection of specific surface markers for T lymphocytes in pleural effusion and ascitic fluid, and by determination of human T cell leukemia virus type I (HTLV-I) proviral DNA integration in mononuclear cells of pleural effusion. This case was considered a rare type of ATL with infiltration of the pleura and peritoneum.

摘要

一名62岁的成年T细胞白血病（ATL）男性患者，主诉厌食和腹部饱胀感。检查发现有腹水和胸腔积液，但无淋巴结肿大、肝脾肿大或皮肤受累。通过检测胸腔积液和腹水中T淋巴细胞的特异性表面标志物，以及测定胸腔积液单核细胞中I型人类T细胞白血病病毒（HTLV-I）前病毒DNA整合情况，确诊为ATL。该病例被认为是一种罕见类型的ATL，伴有胸膜和腹膜浸润。