血红蛋白和肌红蛋白对氧气的易化扩散。
The facilitated diffusion of oxygen by hemoglobin and myoglobin.
作者信息
Rubinow S I, Dembo M
出版信息
Biophys J. 1977 Apr;18(1):29-42. doi: 10.1016/S0006-3495(77)85594-X.
Abstract
We have clarified the use of Wyman's differential equation for the facilitated oxygen flux through a slab of solution of myoglobin or hemoglobin by showing that there is a unique choice of boundary condition on the carrier concentration to be employed in conjunction with it. The singular perturbation solution of Wyman's equation, due to Murrayand Mitchell and Murray, has been extended. By means of it, the paradox of Wittenberg, that the facilitated oxygen flux per mole of heme is apparently independent of the protein carrier, has been resolved.
摘要
通过表明在与怀曼微分方程结合使用时，对于载体浓度存在唯一的边界条件选择，我们已经阐明了该方程在促进氧气通过肌红蛋白或血红蛋白溶液平板的通量方面的应用。默里、米切尔和默里给出的怀曼方程的奇异摄动解得到了扩展。借助于此，维滕贝格悖论，即每摩尔血红素的促进氧气通量显然与蛋白质载体无关，已得到解决。
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本文引用的文献
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Oxygen transport through hemoglobin solutions.氧气通过血红蛋白溶液的传输。
Science. 1960 Feb 26;131(3400):585-90. doi: 10.1126/science.131.3400.585.
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Facilitated diffusion and the possible role of myoglobin as a transport mechanism.易化扩散以及肌红蛋白作为一种转运机制的可能作用。
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The molecular mechanism of hemoglobin-facilitated oxygen diffusion.血红蛋白促进氧气扩散的分子机制。
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Facilitated diffusion of oxygen in the presence of hemoglobin.
Respir Physiol. 1970 Mar;8(3):280-302. doi: 10.1016/0034-5687(70)90037-x.
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Nonequilibrium facilitated oxygen transport in hemoglobin solution.血红蛋白溶液中不平衡促进的氧运输。
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The self-diffusion coefficients of myoglobin and hemoglobin in concentrated solutions.肌红蛋白和血红蛋白在浓缩溶液中的自扩散系数。
J Biol Chem. 1972 Feb 10;247(3):895-901.
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Hemoglobin-facilitated diffusion of oxygen: interfacial and thickness effects.
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Myoglobin-facilitated oxygen diffusion: role of myoglobin in oxygen entry into muscle.肌红蛋白促进的氧气扩散：肌红蛋白在氧气进入肌肉中的作用。
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