Wakker P, Klaassen M P
Medical Decision Making Unit, University of Leiden, The Netherlands.
Health Econ. 1995 Sep-Oct;4(5):373-81. doi: 10.1002/hec.4730040503.
The reduction of costs is becoming increasingly important in the medical field. The relevant topic of many clinical trials is not effectiveness per se, but rather cost-effectiveness ratios. Surprisingly, no statistical tools for analyzing cost-effectiveness ratios have been provided in the medical literature yet. This paper explains the gap in the literature, and provides a first technique for obtaining confidence intervals for cost-effectiveness ratios. The technique does not use sophisticated tools to achieve maximal optimality, but seeks for tractability and ease of application while still satisfying all formal statistical requirements.
成本降低在医学领域正变得越来越重要。许多临床试验的相关主题并非有效性本身，而是成本效益比。令人惊讶的是，医学文献中尚未提供用于分析成本效益比的统计工具。本文解释了文献中的这一空白，并提供了一种获取成本效益比置信区间的初步技术。该技术并非使用复杂工具来实现最大最优性，而是在满足所有正式统计要求的同时，寻求可处理性和易于应用。
