The thalamus of reptiles and mammals: similarities and differences.

Certain aspects of thalamic organization in reptiles and mammals are reviewed. Features shared by the dorsal thalamus of reptiles and that of mammals include projection to the telencephalon, specific and non-specific non-telencephalic afferents, and input from the thalamic reticular nucleus. Differences between the dorsal thalamus of reptiles and that of mammals are the absence of reciprocal telencephalic efferents to the dorsal thalamus and lack of local circuit neurons in reptiles (with the exception of the dorsal geniculate complex in turtles) and their presence in mammals. A thalamic reticular nucleus is present in both reptiles and mammals. In both of these classes of vertebrates, this neuronal aggregate surrounds the dorsal thalamus along its lateral surface, projects to the dorsal thalamus, and is organized into sectors. In one group of reptiles, Caiman crocodilus, the sole reptilian group in which immunocytochemical features have been investigated in detail, the reticular nucleus contains at least three neuronal subpopulations: neurons immunoreactive for glutamic acid decarboxylase (GAD); neurons immunoreactive for parvalbumin; and cells that are not immunoreactive for parvalbumin or, probably, GAD. On the other hand, the reticular nucleus of mammals contains a single population of neurons immunoreactive for GAD, gamma amino butyric acid, and parvalbumin.