Fievez E, Schultze-Balin C, Herbaux B, Dalmas S, Scherpereel P
Département d'Anesthésie-Réanimation Chirurgicale 2, Centre Hospitalier Régional, Universitaire de Lille.
Cah Anesthesiol. 1995;43(5):425-33.
A retrospective study including 319 patients was realized from 1984 to 1993 in order to evaluate during scoliosis surgery the incidence on bleeding of the type of scoliosis and the anesthetic procedure. Blood losses were below one litre thus reducing the homologous blood transfusions. The patient was in prone position on a modified Wilson frame which facilitates venous return from the dorsal region. A moderate controlled hypotension was realized by combination of halothane, intravenous nitroglycerin (NG) and beta-blocking drugs (when required). Somatosensory evoked potentials were continuously monitored during surgery. A compression of the dorsal region was realized postoperatively in order to reduce blood loss. The blood losses were compared using Student's t-test. The mean perioperative bleeding was 9.8 ml.kg-1 for idiopathic scoliosis (no transfusion required), 14.1 ml.kg-1 for secondary scoliosis (p < 0.05 vs idiopathic) and 29.3 ml.kg-1 for neuromyopathic scoliosis (p < 0.05 vs idiopathic), indicating a major influence of muscle atonia on bleeding. The moderate controlled hypotension by iterative injection of NG and beta-adrenergic blocking drugs provided a safe and reversible hypotension.
1984年至1993年对319例患者进行了一项回顾性研究,以评估脊柱侧弯手术期间脊柱侧弯类型和麻醉方法对出血的影响。失血量低于1升,从而减少了异体输血。患者俯卧在改良的威尔逊架上,这有助于背部区域的静脉回流。通过氟烷、静脉注射硝酸甘油(NG)和β受体阻滞剂(必要时)联合使用实现中度控制性低血压。手术期间持续监测体感诱发电位。术后对背部区域进行压迫以减少失血。使用学生t检验比较失血量。特发性脊柱侧弯的围手术期平均失血量为9.8 ml·kg-1(无需输血),继发性脊柱侧弯为14.1 ml·kg-1(与特发性脊柱侧弯相比,p<0.05),神经肌肉性脊柱侧弯为29.3 ml·kg-1(与特发性脊柱侧弯相比,p<0.05),表明肌肉弛缓对出血有重大影响。通过反复注射NG和β肾上腺素能阻滞剂进行的中度控制性低血压提供了一种安全且可逆的低血压。