Evans J L, Ng K H, Wiet S G, Vonesh M J, Burns W B, Radvany M G, Kane B J, Davidson C J, Roth S I, Kramer B L, Meyers S N, McPherson D D
Department of Medicine, Northwestern University Medical School, Chicago, Ill, USA.
Circulation. 1996 Feb 1;93(3):567-76. doi: 10.1161/01.cir.93.3.567.
The geometrical accuracy of conventional three-dimensional (3D) reconstruction methods for intravascular ultrasound (IVUS) data (coronary and peripheral) is hampered by the inability to register spatial image orientation and by respiratory and cardiac motion. The objective of this work was the development of improved IVUS reconstruction techniques.
We developed a 3D position registration method that identifies the spatial coordinates of an in situ IVUS catheter by use of simultaneous ECG-gated biplane digital cinefluoroscopy. To minimize distortion, coordinates underwent pincushion correction and were referenced to a standardized calibration cube. Gated IVUS data were acquired digitally, and the spatial locations of the imaging planes were then transformed relative to their respective 3D coordinates, rendered in binary voxel format, resliced, and displayed on an image-processing workstation for off-line analysis. The method was tested by use of phantoms (straight tube, 360 degrees circle, 240 degrees spiral) and an in vitro coronary artery model. In vivo feasibility was assessed in patients who underwent routine interventional coronary procedures accompanied by IVUS evaluation. Actual versus calculated point locations were within 1.0 +/- 0.3 mm of each other (n = 39). Calculated phantom volumes were within 4% of actual volumes. Phantom 3D reconstruction appropriately demonstrated complex morphology. Initial patient evaluation demonstrated method feasibility as well as errors if respiratory and ECG gating were not used.
These preliminary data support the use of this new method of 3D reconstruction of vascular structures with use of combined vascular ultrasound data and simultaneous ECG-gated biplane cinefluoroscopy.
传统的用于血管内超声（IVUS）数据（冠状动脉和外周血管）的三维（3D）重建方法的几何准确性受到无法记录空间图像方向以及呼吸和心脏运动的阻碍。这项工作的目的是开发改进的IVUS重建技术。
我们开发了一种3D位置配准方法，该方法通过使用同步心电图门控双平面数字荧光透视术来识别原位IVUS导管的空间坐标。为了使失真最小化，对坐标进行了枕形校正，并以标准化校准立方体为参考。门控IVUS数据以数字方式采集，然后将成像平面的空间位置相对于其各自的3D坐标进行变换，以二进制体素格式渲染，重新切片，并显示在图像处理工作站上进行离线分析。该方法通过使用模型（直管、360度圆、240度螺旋）和体外冠状动脉模型进行测试。在接受常规冠状动脉介入手术并伴有IVUS评估的患者中评估了体内可行性。实际点位置与计算点位置之间的误差在1.0±0.3毫米以内（n = 39）。计算的模型体积在实际体积的4%以内。模型的3D重建适当地显示了复杂的形态。初步的患者评估证明了该方法的可行性以及如果不使用呼吸和心电图门控时的误差。
这些初步数据支持使用这种结合血管超声数据和同步心电图门控双平面荧光透视术的血管结构3D重建新方法。
