与枸橼酸镓-67相比，用锝-99m（V）二巯基丁二酸和枸橼酸锝-99m对肺结核进行显像。

The visualization of pulmonary tuberculosis with Tc-99m (V) DMSA and Tc-99m citrate in comparison to Ga-67 citrate.

作者信息

Gulaldi N C, Bayhan H, Ercan M T, Kibar M, Oztürk B, Oğretensoy M, Bekdik C F

机构信息

Department of Nuclear Medicine, Hacettepe University Medical Faculty, Ankara, Turkey.

出版信息

Clin Nucl Med. 1995 Nov;20(11):1012-4. doi: 10.1097/00003072-199511000-00017.

DOI:10.1097/00003072-199511000-00017

PMID:8565355

Abstract

Two patients with active tuberculosis confirmed by chest radiography and positive sputum smears were included in this study to determine whether a Tc-99m labeled agent, such as DMSA or citrate could localize such lesions in comparison to Ga-67 citrate. Both patients had Tc-99m (V) DMSA, Tc-99m citrate, and Ga-67 citrate scanning at 1-day to 5-day intervals. Both patients had positive scan findings with all three radiopharmaceuticals. However, the quality of Tc-99m (V) DMSA scans was superior to Tc-99m citrate, which showed faint uptake. Tc-99m (V) DMSA may be a better alternative to Ga-67 citrate in the assessment of the activity and extent of tuberculosis.

摘要

两名经胸部X光检查确诊为活动性肺结核且痰涂片呈阳性的患者被纳入本研究，以确定与枸橼酸镓-67相比，锝-99m标记的试剂，如二巯基丁二酸（DMSA）或枸橼酸盐，是否能使此类病变显影。两名患者均在1至5天的间隔内进行了锝-99m（V）二巯基丁二酸、锝-99m枸橼酸盐和枸橼酸镓-67扫描。两名患者使用这三种放射性药物扫描结果均为阳性。然而，锝-99m（V）二巯基丁二酸扫描的质量优于锝-99m枸橼酸盐扫描，后者摄取显示微弱。在评估结核病的活动性和范围方面，锝-99m（V）二巯基丁二酸可能是枸橼酸镓-67的更好替代品。