[Changes in myocardial ATPase activity and Ca2+ content in burned rats].

The myocardial ATPase activity and Ca2+ content were investigated in rats with full thickness skin burn injury of 30% TBSA. The results showed that there were significant inhibitions of Na+, K(+)-ATPase,Ca2+, Mg(2+)-ATPase, and Ca(2+)-ATPase activities of myocardium after burn injury. The burn injury could result in increase of calcium content in myocardium. Burned rats also had a higher level of MDA in heart tissue when compared to controls. This study demonstrates that the membrane defects with respect to ATPase activity, oxygen free radical, and Ca2+ overload in myocardium may be associated with damage of myocardium after burns.