与腺病毒5型和7型相关的脱氧核糖核酸酶活性

Deoxyribonuclease activity associated with adenovirus 5 and 7.

作者信息

Cajean-Feroldi C, Chardonnet Y, Chantepie-Auray J

出版信息

Eur J Biochem. 1977 Apr 15;74(3):457-62. doi: 10.1111/j.1432-1033.1977.tb11412.x.

DOI:10.1111/j.1432-1033.1977.tb11412.x

Abstract

A DNase activity was found associated with isolated components of adenovirus types 5 and 7. The enzymatic activity was associated with the purified virus and viral components extracted from the soluble material of infected cells. The DNase activity of adenovirus type 5 was maximum at pH 5.5 and 7.0 whereas adenovirus 7 was active only at pH 7.0. Both DNases were shown to be located in the penton fraction.

摘要

发现5型和7型腺病毒的分离成分具有脱氧核糖核酸酶（DNase）活性。这种酶活性与纯化病毒以及从感染细胞可溶性物质中提取的病毒成分有关。5型腺病毒的DNase活性在pH 5.5和7.0时最高，而7型腺病毒仅在pH 7.0时有活性。两种DNase均显示位于五邻体组分中。