Fundam Clin Pharmacol. 1995;9(4):384-6. doi: 10.1111/j.1472-8206.1995.tb00514.x.
The Ottawa Stroke Trials Registry (OSTR) collects information on all randomized controlled trials (RCTs), in all languages, in which the primary focus is stroke. Published trials are added to the registry database once they have been identified by volunteers hand searching journals. We undertook this study to assess volunteer sensitivity, specificity, positive and negative predictive values, accuracy and reliability in identifying RCTs. Three volunteers participated in this study. The complete contents of five years of one journal were searched (n = 240) as were ten research reports from five journals. Volunteer sensitivity, specificity, positive and negative predictive values, and accuracy was 89.5%, 100%, 100%, 99.1%, and 99% respectively. Inter volunteer reliability was 0.87. Searching the published literature to identify RCTs is an enormous task. These results indicate that volunteers, with minimal training, can effectively contribute to this endeavour.
渥太华中风试验注册库（OSTR）收集所有主要关注中风的随机对照试验（RCT）的信息，无论语言。一旦志愿者通过手工检索期刊识别出已发表的试验，就会将其添加到注册库数据库中。我们开展这项研究以评估志愿者在识别随机对照试验时的敏感性、特异性、阳性和阴性预测值、准确性和可靠性。三名志愿者参与了这项研究。对一份期刊五年的全部内容（n = 240）以及来自五份期刊的十份研究报告进行了检索。志愿者的敏感性、特异性、阳性和阴性预测值以及准确性分别为89.5%、100%、100%、99.1%和99%。志愿者之间的可靠性为0.87。通过检索已发表文献来识别随机对照试验是一项艰巨的任务。这些结果表明，经过最少培训的志愿者能够有效地为这项工作做出贡献。
