Suppr超能文献

人体测量学指标在评估冠心病风险中的应用:工作场所健康筛查的有用工具?

Use of anthropometric measurements in assessing risk for coronary heart disease: a useful tool in worksite health screening?

作者信息

Oshaug A, Bugge K H, Bjønnes C H, Ryg M

机构信息

Nordic School of Nutrition, University of Oslo, Norway.

出版信息

Int Arch Occup Environ Health. 1995;67(6):359-66. doi: 10.1007/BF00381049.

Abstract

The study examined the association between the anthropometric measurements body mass index (BMI), waist/hip ratio (WHR), and waist/thigh ratio (WTR) and cardiovascular risk factors, and assessed whether a combination of BMI and WHR could be used in routine screening of risk for cardiovascular arteriosclerotic disease at worksites. The data were obtained from a cross-sectional survey designed to assess the nutritional situation, with special reference to cardiovascular risk factors. The study population comprised 372 healthy men working on platforms in the North Sea. Serum cholesterol, triglyceride, fibrinogen, and blood pressure were positively related to the anthropometric variables, while high-density lipoprotein (HDL) was inversely related with them. The relations remained after adjusting for possible confounders, such as age, smoking, physical activity, and an indicator of dietary fat intake. In stepwise multiple linear regression models, BMI, WHR, and WTR were positively related to serum cholesterol, triglycerides, fibrinogen, diastolic blood pressure, and systolic blood pressure, and inversely related to HDL. When controlling for the anthropometric variables WHR and WTR, BMI was not independently related to fibrinogen and risk score. WHR and WTR were not independently related to systolic and diastolic blood pressure, and WTR was in addition not related to triglycerides when controlling for BMI. Overall, the anthropometric variables BMI and WHR were considered the best predictors for CAD risk when taking several risk factors into consideration. A joint variable between BMI and WHR, called "body score", constituted the four categories lean, lean android, overweight gynoid, and overweight ovoid. This body score was positively associated with levels of serum lipids, fibrinogen, and blood pressure, and inversely associated with HDL. In stepwise multiple linear regression models, controlling for possible confounding variables, body score was positively related to CAD risk. Dividing the risk score into tertiles, about 51% of the lean were in the first, while 46% of the overweight ovoid were in the third tertile. Those classified as lean android or overweight gynoid had about the same distribution, namely between 31% and 39% in each tertile if the two categories were combined. These data support the hypothesis that BMI, WHR, and WTR are independent predictors for risk factors for CAD among oil workers, and that combinations of BMI and WHR are strong enough predictors to be useful in routine screening for CAD risk at worksites. Based on these findings, supported by data from the literature, a matrix aimed at screening for follow-up at worksites is proposed.

摘要

该研究考察了人体测量指标体重指数(BMI)、腰臀比(WHR)和腰大腿比(WTR)与心血管危险因素之间的关联,并评估BMI和WHR的组合是否可用于在工作场所对心血管动脉硬化疾病风险进行常规筛查。数据来自一项旨在评估营养状况的横断面调查,特别关注心血管危险因素。研究人群包括372名在北海平台工作的健康男性。血清胆固醇、甘油三酯、纤维蛋白原和血压与人体测量变量呈正相关,而高密度脂蛋白(HDL)与它们呈负相关。在对年龄、吸烟、身体活动和饮食脂肪摄入指标等可能的混杂因素进行调整后,这些关系依然存在。在逐步多元线性回归模型中,BMI、WHR和WTR与血清胆固醇、甘油三酯、纤维蛋白原、舒张压和收缩压呈正相关,与HDL呈负相关。在控制人体测量变量WHR和WTR时,BMI与纤维蛋白原和风险评分无独立关联。WHR和WTR与收缩压和舒张压无独立关联,并且在控制BMI时,WTR与甘油三酯也无关联。总体而言,在考虑多个危险因素时,人体测量变量BMI和WHR被认为是CAD风险的最佳预测指标。BMI和WHR之间的一个联合变量,称为“身体评分”,分为瘦型、瘦苹果型、超重梨型和超重卵形四类。该身体评分与血清脂质、纤维蛋白原和血压水平呈正相关,与HDL呈负相关。在逐步多元线性回归模型中,在控制可能的混杂变量后,身体评分与CAD风险呈正相关。将风险评分分为三分位数,约51%的瘦型人群处于第一分位数,而46%的超重卵形人群处于第三分位数。那些被归类为瘦苹果型或超重梨型的人群分布大致相同,如果将这两类合并,每一分位数中的比例在31%至39%之间。这些数据支持以下假设:BMI、WHR和WTR是石油工人中CAD危险因素的独立预测指标,并且BMI和WHR的组合是足够强的预测指标,可用于在工作场所对CAD风险进行常规筛查。基于这些发现,并得到文献数据的支持,提出了一个旨在在工作场所进行后续筛查的矩阵。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验