Meola M, Giuliano G, Morelli E, Cupisti A, Barsotti G
Chair of Nephrology, Università di Pisa, Italy.
Nephron. 1995;71(2):143-8. doi: 10.1159/000188702.
The aim of this study was to evaluate whether a stimulated diuresis test associated with ultrasound is able to differentiate pelvic dilation due to atonicity from pelviureteric junction obstruction (PUO). 42 patients (25 f, 17 m) with minimal or moderate renal pelvis dilation revealed by sonography were selected for the test. Three different measurements of the anteroposterior diameter (APD) of the renal pelvis were done at the renal hilus level, by using a transversal ultrasound scan: the first under spontaneous diuresis conditions, the second after hydration with 1.5 liters of water, and the third with a full bladder 15 min after intravenous injection of 20 mg frusemide. All the patients underwent pyelography. Baseline APD (bAPD) linearly correlated with the PAD both after hydration and frusemide (r = 0.89 and r = 0.84, respectively). A descriptive evaluation of the frequency distribution of the bAPD suggested the possibility that the data samples could belong to three populations with different underlying pathophysiological conditions. Correspondence analysis between bAPD distribution and PUO suggested that the best grouping of data was: group 1 (11 patients) bAPD < 13 mm, group 2 (14 patients) 13 > or = bAPD < or = 20 mm, group 3 (17 patients) bAPD > 20 mm (likelihood ratio chi 2 46.36; d.f. = 2). Standard intravenous pyelography showed an increase in pelvis size compatible with PUO in 2 patients from group 2 and in all patients from group 3.(ABSTRACT TRUNCATED AT 250 WORDS)
本研究的目的是评估与超声相关的刺激利尿试验能否区分因张力缺乏导致的盆腔扩张与肾盂输尿管连接处梗阻(PUO)。选择了42例经超声检查显示有轻度或中度肾盂扩张的患者(25例女性,17例男性)进行该试验。通过横向超声扫描,在肾门水平对肾盂前后径(APD)进行三种不同测量:第一次在自然利尿条件下,第二次在饮用1.5升水后,第三次在静脉注射20毫克速尿15分钟后膀胱充盈时。所有患者均接受了肾盂造影。基线APD(bAPD)与水化后和速尿后的PAD均呈线性相关(分别为r = 0.89和r = 0.84)。对bAPD频率分布的描述性评估表明,数据样本可能属于具有不同潜在病理生理状况的三个总体。bAPD分布与PUO之间的对应分析表明,数据的最佳分组为:第1组(11例患者)bAPD < 13毫米,第2组(14例患者)13≤bAPD <或= 20毫米,第3组(17例患者)bAPD > 20毫米(似然比卡方46.36;自由度 = 2)。标准静脉肾盂造影显示,第2组的2例患者和第3组的所有患者的肾盂大小增加,符合PUO。(摘要截断于250字)