芳基和杂芳基磺酰腙的抗惊厥活性。
Anticonvulsant activity of aryl and hetarylsulfonylhydrazones.
作者信息
Darias V, Abdallah S, Delgado L, Vega S
机构信息
Departamento de Farmacología, Facultad de Farmacia, Universidad de La Laguna, Tenerife, Spain.
出版信息
Pharmazie. 1995 Nov;50(11):756-8.
PMID:8570673
Abstract
A series of aryl and hetarylsulfonylhydrazones of aromatic aldehydes were tested for acute toxicity and anticonvulsant activity in mice. Some of these compounds were effective in the MES, pentetrazol and strychnine tests. Thiophene derivatives were the most active terms of the series.
摘要
对一系列芳香醛的芳基和杂芳基磺酰腙进行了小鼠急性毒性和抗惊厥活性测试。其中一些化合物在最大电休克（MES）、戊四氮和士的宁测试中有效。噻吩衍生物是该系列中活性最高的。
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