Visible light anaerobic photoconversion of tyrosine sensitized by riboflavin. Cytotoxicity on mouse tumoral cells.
作者信息
Silva E, Fürst S, Edwards A M, Becker M I, De Ioannes A E
机构信息
Facultad de Química (536), P. Universidad Católica de Chile, Santiago, Chile.
出版信息
Photochem Photobiol. 1995 Dec;62(6):1041-5. doi: 10.1111/j.1751-1097.1995.tb02406.x.
Abstract
The anaerobic phototransformation of tyrosine under visible light sensitized by riboflavin is reported. The cytotoxicity of the anaerobic photoproducts on in vitro-cultured myeloid mouse tumoral cells was demonstrated. A radical mechanism is proposed. Dityrosine was identified as one of the main anaerobic photoproducts by using absorption, emission and 1H-NMR spectra.
摘要
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