Neau D, Monlun E, Delmas M, Beylot C, Longy-Boursier M, Le Bras M
Service de médecine interne et tropicale, hôpital Saint-André, Bordeaux, France.
Rev Med Interne. 1995;16(12):919-22. doi: 10.1016/0248-8663(96)80813-7.
Sweet's syndrome is an acute febrile neutrophilic dermatosis. Although it frequently appears as an idiopathic disorder, it may occur in association, often as presenting sign, with malignancy or more rarely with infections. We report two cases of Sweet's syndrome preceded by digestive infection due to Yersinia enterocolitica, affirmed by significant rises in serum antibody titers. Other nongastrointestinal manifestations of such infections are known, predominantly arthritis and erythema nodosum. Sweet's syndrome is a rare complication of these infections. Treatment with systemic steroids, usually effective, can be replaced by antibiotics with apparently favorable results. The search of an infectious origin should be systematic in cases of Sweet's syndrome that appear to be idiopathic.
斯威特综合征是一种急性发热性嗜中性皮病。尽管它常表现为特发性疾病,但也可能与恶性肿瘤相关,常作为首发症状出现,或更罕见地与感染有关。我们报告了两例由小肠结肠炎耶尔森菌引起的消化感染前驱的斯威特综合征病例,血清抗体滴度显著升高证实了这一点。已知此类感染的其他非胃肠道表现主要是关节炎和结节性红斑。斯威特综合征是这些感染的罕见并发症。通常有效的全身用类固醇治疗可被抗生素替代,效果明显良好。对于看似特发性的斯威特综合征病例,应系统地寻找感染源。