Ly S, Beylot-Barry M, Beyssac R, Doutre M S, Beylot C
Service de dermatologie, CHU de Bordeaux, hôpital du Haut-Lévêque, Pessac, France.
Rev Med Interne. 1995;16(12):931-3. doi: 10.1016/0248-8663(96)80816-2.
The association of Sweet's syndrome and Crohn's disease is rare. We report a new case of such association. A 45 year-old woman developed a diarrhea, fever, and skin lesions consistent with a presumptive diagnosis of Sweet's syndrome. Crohn's disease was also diagnosed. Oral prednisone, associated with mesalazine, effected improvement of both cutaneous lesions and bowel disease. The ten cases of the literature and ours show that Sweet's syndrome may occur during an acute phase of Crohn's disease. Most of the time, Crohn's disease has already been diagnosed. However, this was not so with our patient, wherein lies the originality of our case. A general corticotherapy is the preferred course of treatment.
斯威特综合征与克罗恩病的关联罕见。我们报告了这样一例新的关联病例。一名45岁女性出现腹泻、发热及符合斯威特综合征初步诊断的皮肤损害。同时也诊断出了克罗恩病。口服泼尼松联合美沙拉嗪使皮肤损害和肠道疾病均得到改善。文献中的10例病例及我们的病例表明,斯威特综合征可能发生在克罗恩病的急性期。大多数情况下,克罗恩病此前已被诊断。然而,我们的患者并非如此,这也是我们病例的独特之处。全身皮质类固醇疗法是首选的治疗方案。