Friedli P
Schweiz Arch Neurol Neurochir Psychiatr. 1977;120(1):11-25.
The results of a retrospective study on 835 patients in which brain scan was performed during their ambulant and clinical examination are presented. In 18.6% of the cases the scan gave correct results which highly determined the further diagnostic procedure. In 37.5% of the cases the radioisotope brain scan revealed positive results which besides other findings contributed to the decision on the further diagnostic procedure. In 30.5% of the cases the results of the scan were correct but of low diagnostic value, since the further procedure was determined by other diagnostic methods. In 7.4% of the cases the brain scan gave false positive results indicating a focal brain lesion. In these cases the cerebral scintigraphy gave rise to redundant and riskful neuroradiological investigations. In 1.8% of the cases in which retrospectively a threatening brain lesion could be established, the brain scan gave false negative results. The results of this investigation indicate that brain scanning although being a harmless diagnostic method, can induce redundant and riskful further examination. The application of isotope brain scan as diagnostic procedure requires a precise indication even more so, since computerized transverse axial tomography, a harmless screening method of high resolution is now available.
本文呈现了一项针对835例患者的回顾性研究结果,这些患者在门诊及临床检查期间均接受了脑部扫描。在18.6%的病例中,扫描结果正确,这对进一步的诊断程序起到了高度决定性作用。在37.5%的病例中,放射性同位素脑部扫描显示出阳性结果,除其他发现外,这些结果有助于决定进一步的诊断程序。在30.5%的病例中,扫描结果正确但诊断价值较低,因为进一步的程序是由其他诊断方法决定的。在7.4%的病例中,脑部扫描出现假阳性结果,提示存在局灶性脑病变。在这些病例中,脑闪烁显像导致了多余且有风险的神经放射学检查。在1.8%的病例中,回顾性分析可确定存在威胁性脑病变,但脑部扫描却给出了假阴性结果。这项研究的结果表明,尽管脑部扫描是一种无害的诊断方法,但可能会导致多余且有风险的进一步检查。同位素脑部扫描作为一种诊断程序,更需要精确的指征,因为现在有了计算机断层扫描,这是一种无害的高分辨率筛查方法。