Lanier L L
DNAX Research Institute of Molecular and Cellular Biology, Palo Alto, USA.
Curr Opin Immunol. 1995 Oct;7(5):626-31. doi: 10.1016/0952-7915(95)80068-9.
Natural killer cells express receptors for polymorphic MHC class I molecules that inhibit cytotoxicity mediated by natural killer cells. The genes encoding the mouse and human natural killer cell receptors for MHC class I have recently been cloned, and there is rapid progress in elucidating their structure and function. These receptors may be important in bone marrow transplantation and explain the phenomenon of hybrid resistance.
自然杀伤细胞表达针对多态性MHC I类分子的受体，这些受体可抑制自然杀伤细胞介导的细胞毒性。编码小鼠和人类MHC I类自然杀伤细胞受体的基因最近已被克隆，在阐明其结构和功能方面取得了迅速进展。这些受体在骨髓移植中可能很重要，并可解释杂种抗性现象。
