von Lieven H, Lissner J
Strahlentherapie. 1977 Apr;153(4):245-56.
Sole irradiation treatment for renal carcinoma or its metastases has to be regarded as only a palliative therapy, whereas postoperative radiation therapy brings about a distinct diminution of the frequency of local recurrences, and, at least in advanced tumor stages, an improvement of the 5-year survival rate. Long-term preirradiation (ca 3000 rd TD within 3 weeks, and operation after another three weeks) or short-term pre-irradiation (ca 1200 to 2000 rd TD within 2 or 4 days, and operation the next day) are tolerated well and do involve no disturbances of the wound healing. Surgical treatment is not complicated by short-term irradiation, but often is easier following long-term irradiation; beyond this, the latter may just render possible a radical extirpation of the renal tumor. It appears from first results that decrease of distant spread and improvement of recovery rates in advanced tumor stages may be within reach, particularly in connection with post-operative irradiation.
单独的放射治疗对于肾癌及其转移灶而言只能被视为一种姑息疗法,而术后放射治疗能显著降低局部复发的频率,并且至少在肿瘤晚期能提高5年生存率。长期术前放疗(3周内给予约3000拉德的肿瘤剂量,再过3周后进行手术)或短期术前放疗(2或4天内给予约1200至2000拉德的肿瘤剂量,次日进行手术)耐受性良好,且不会干扰伤口愈合。手术治疗不会因短期放疗而变得复杂,但长期放疗后往往更容易进行;除此之外,长期放疗还可能使肾肿瘤的根治性切除成为可能。初步结果显示,在晚期肿瘤阶段,减少远处转移和提高康复率是有可能实现的,尤其是与术后放疗相结合时。